What is the pathophysiological basis for narcolepsy or hypersomnolence?
I’m trying to understand these conditions beyond textbook exerpt and internet sites describing narcolepsy in scant detail. Please help provide some more details if you can. I am highly interested in these disorders and what exactly causes them. Also, what is the best treatment?
Tags: basis, pathophysiological basis, hypersomnolence, pathophysiological, Narcolepsy, exerptRelated posts:
Narcolepsy is thought to result from genetic predisposition, abnormal neurotransmitter functioning and sensitivity, and abnormal immune modulation. Current data implicate certain human leukocyte antigen (HLA) subtypes and abnormalities in monoamine synaptic transmission, particularly in the pontine reticular activating system.